ABSTRACT
Objective:To analyze the prevalence of syphilis infection and influence factors of syphilis infection among the male STD attendants in Songyuan City of Jilin Province, and to provide theoretical basis for the development and implementation of syphilis intervention policy.Methods:A questionnaire survey and serological tests were conducted among the men who went to STD clinic for treatment in the ZhanDong Dermatology Specialist Hospital or Qianguo County Hospital in Songyuan City from 2011 to 2015.Chi-square test was performed to compare the prevalences of syphilis infection between different groups.Multivariable Logistic regression model was used to find the independent factors of syphilis infection among the male STD attendants.Results:Of all 2 000 male STD attendants who involved in the study,the mean age was (34.50±9.03)years old.218 persons (10.90%)of them had sexual behavior with female sex workers in the last three months,433 persons (21.65%)of them had temporary sexual behavior in the last three months,42 persons (2.10%)of them had homosexual behavior in the last three months.Of the respondents,238 persons (11.90%)had a previous diagnosis of sexually transmitted diseases,86 persons of them had gonorrhea (36.13%),43 persons had syphilis (18.07%),15 persons had genital tract Chlamydia (6.30%),55 persons had genital herpes (23.11%),40 persons had genital herpes (16.81%),and 1 person had combined infection of gonorrhea and syphilis. The prevalence of syphilis of 2 000 male STD attendants was 6.4%.From 2011 to 2015,there was a decrease in the prevalences of syphilis (χ2 =44.25,P <0.001).In the last 3 months, the risk of the male STD attendants who had commercial sex with prostitute,temporary sex behavior,homosexual behavior and a history of STD infection to be infected with syphilis in the past were 3.75 times (OR= 3.75,95% CI:2.46 - 5.71),2.31 times (OR = 2.31,95% CI: 1.56 - 3.41),2.97 times (OR=2.97,95%CI:1.33-6.64)and 1.69 times (OR=1.69,95%CI:1.07-2.67)than those who did not have those behaviors,respectively. Conclusion:There is a significantly decreasing tendency in the prevalence of syphilis among the male STD attendants in Songyuan City in the past 5 years.The high risk sexual behaviors are the main influence factors of syphilis infection among them.
ABSTRACT
To construct a new biomaterial-small intestinal submucosa coated with gelatin hydrogel incorporating basic fibroblast growth factor, and to evaluate the new biomaterials for the reconstruction of abdominal wall defects. Thirty six Sprague-Dawley rats were used in the animal experiments and randomly divided into three groups. The new biomaterial was constructed by combining small intestinal submucosa with gelatin hydrogel for basic fibroblast growth factor release. Abdominal wall defects were created in rats, and repaired using the new biomaterials (group B), compared with small intestinal submucosa (group S) and ULTRAPROTM mesh (group P). Six rats in each group were sacrificed at three and eight weeks postoperatively to examine the gross effects, inflammatory responses, collagen deposition and neovascularization. After implantation, mild adhesion was caused in groups B and S. Group B promoted more neovascularization than group S at three weeks after implantation, and induced significantly more amount of collagen deposition and better collagen organization than groups S and P at eight weeks after implantation. Small intestinal submucosa coated with gelatin hydrogel incorporating basic fibroblast growth factor could promote better regeneration and remodeling of host tissues for the reconstruction of abdominal wall defects.